GRAPE SEED EXTRACT SUPPRESSES CALCITONIN GENE-RELATED PEPTIDE SECRETION AND UPREGULATES EXPRESSION OF GAD 65/67 AND GABAB RECEPTOR IN PRIMARY TRIGEMINAL GANGLION CULTURES

Grape seed extract suppresses calcitonin gene-related peptide secretion and upregulates expression of GAD 65/67 and GABAB receptor in primary trigeminal ganglion cultures

The trigeminal ganglion is implicated in the underlying pathology of migraine and temporomandibular joint disorders (TMD), Quantum Mechanix which are orofacial pain conditions involving peripheral and central sensitization.The neuropeptide calcitonin gene-related peptide (CGRP) is synthesized in some trigeminal ganglion neurons, and its release pro

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Design of New Submerged Ozone Generator

In order to meet the demand of adjustable ozone concentration and reduce energy consumption, a new submerged ozone generator was designed.The nozzle, reaction chamber and electrode plate were studied and optimized.The mechanical structure design of the device was Collections completed.The electrical circuit model was built by Matlab/Simulink, the d

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A rare case of intusscusception in a 6-month-old baby

This case report discusses the clinical presentation, imaging findings, and successful management of a rare case of intussusception in a 6-month-old female infant referred to a regional hospital in Ghana.The patient presented with vomiting, lethargy, fever, and currant jelly stool.Differential diagnoses considered included Merkel diverticulum, volv

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